Welcome to the Saier Lab
Our laboratory takes a multidisciplinary approach to science, using biochemical, molecular genetic, physiological, and bioinformatic approaches. We have three primary research interests, one concerned with transcriptional and metabolic regulation in bacteria, a second with transport protein evolution, and a third with the recently identified process of transposon-mediated directed mutation. We also created and now maintain the Transporter Classification DataBase (TCDB), which was adopted by the International Union of Biochemistry and Molecular Biology (IUBMB) as the primary source of information relating to molecular transport.
About us
Dr. Milton Saier is the head of the laboratory. The lab has two main branches: the wet lab (led by Dr. Zhongge Zhang) and the dry lab (led by Dr. Arturo Medrano-Soto). The progress of our experimental and bioinformatic projects depends on the work and interaction within our wonderfully eclectic Team of researchers, talented students, visiting scholars and external collaborators. For more details, please visit our Research and Publications pages. The software developed and maintained by our bioinformatics team is available in our GitHub repository and our web applications are available in our BioTools page, Please, do not hesitate to contact us If you have any questions/requests or if you would like to give usĀ feedback.

Latest News
Hot off the press
Our collaborator Dr. Reddy and Dr. Saier just published a review in the journal Microbial Physiology where they discus the relationship between eating meat and epidemics. The title is "The Causal Relationship between Eating Animals and Viral Epidemics". For your...
Hot off the press
Grad students S. C. Wang, P. Davejan, K. J. Hendargo, I. Javadi-Razaz, Amy Chou, D. C. Yee, F. Ghazi, K. J. K. Lam, A. M. Conn, A. Madrigal, Dr. Medrano-Soto and Dr. Saier just published a paper in the journalĀ Biochimica et Biophysica Acta (BBA) - Biomembranes about...
Hot off the press
Dr. Medrano-Soto, grad student F. Ghazhi, grad student K. J. Hendargo, collaborator Dr. Moreno-Hagelsieb, grad student S. Myers and Dr. Saier just published a paper in the journal PLOS ONE about the expansion of the TOG Superfamily. The title is: "Expansion of the...