Welcome to the Saier Lab
Our laboratory takes a multidisciplinary approach to science, using biochemical, molecular genetic, physiological, and bioinformatic approaches. We have three primary research interests, one concerned with transcriptional and metabolic regulation in bacteria, a second with transport protein evolution, and a third with the recently identified process of transposon-mediated directed mutation. We also created and now maintain the Transporter Classification DataBase (TCDB), which was adopted by the International Union of Biochemistry and Molecular Biology (IUBMB) as the primary source of information relating to molecular transport.
About us
Dr. Milton Saier is the head of the laboratory. The lab has two main branches: the wet lab (led by Dr. Zhongge Zhang) and the dry lab (led by Dr. Arturo Medrano-Soto). The progress of our experimental and bioinformatic projects depends on the work and interaction within our wonderfully eclectic Team of researchers, talented students, visiting scholars and external collaborators. For more details, please visit our Research and Publications pages. The software developed and maintained by our bioinformatics team is available in our GitHub repository and our web applications are available in our BioTools page, Please, do not hesitate to contact us If you have any questions/requests or if you would like to give us feedback.
Latest News
Hot off the press
Students Jianing Wang, Kevin J Hendargo, Katie Jing Kay Lam, Dai Ngoc Trang Dao, and Drs. Arturo Medrano, Milton Saier just published the paper "Comparative Genomics of Viral Genomes and Identification of Three Novel Viroporin-Like Superfamilies" in the journal...
Hot off the press
Students Jack William Ord, Janie Wu, Sofia Smith, Zhenhao Feng, Keisha Ancheta, Luis Fernando Garrido, Ge Yao, Sahil Gupta, Ethan T Lee, and Drs. Zhongge Zhand and Milton Saier just published the paper "Investigating the Trans Effects of IS1 Transposases on...
Hot off the press
Collaborator Dr. Lakshmi Reddy and Dr. Milton Saier just published the review: "Microbiome: Friend or Friendly Foe" in the journal Microbial Physiology. For your convenience, this is the link to PubMed. Abstract: The human microbiome is a dynamic, polymicrobial...