Welcome to the Saier Lab

Our laboratory takes a multidisciplinary approach to science, using biochemical, molecular genetic, physiological, and bioinformatic approaches. We have three primary research interests, one concerned with transcriptional and metabolic regulation in bacteria, a second with transport protein evolution, and a third with the recently identified process of transposon-mediated directed mutation. We also created and now maintain the Transporter Classification DataBase (TCDB), which was adopted by the International Union of Biochemistry and Molecular Biology (IUBMB) as the primary source of information relating to molecular transport.

 

Our Research

About us

Dr. Milton Saier is the head of the laboratory. The lab has two main branches: the wet lab (led by Dr. Zhongge Zhang) and the dry lab (led by Dr. Arturo Medrano-Soto). The progress of our experimental and bioinformatic projects depends on the work and interaction within our wonderfully eclectic team of researchers, talented students, visiting scholars and external collaborators. For more details, please visit our Research and Publications pages. The software developed and maintained by our bioinformatics team is available in our GitHub repository and our web applications are available in our BioTools page, Please, do not hesitate to contact us If you have any questions/requests or if you would like to give us  feedback.

Latest News

Best bioinformatics figure

Best bioinformatics figure

Congratulations to our grad student Kevin J. Hendargo, and all coauthors of our recently published paper reporting a comparative genomics study within the Asgard archaeal supephylum, for winning the 2021 best bionformatics figure for the Biological Science Division...

Hot off the press

Hot off the press

Dr. Saier and colleagues Drs. S. Chowdhury, S. Hepper, MK Lodi, and P. Uetz just published a paper in the journal Proteomes. The title is: "The Protein Interactome of Glycolysis in Escherichia coli.". For your convenience, this is the link to PubMed.   Abstract...

Hot off the press

Hot off the press

MSc S.  Russum, grad students K. J. K. Lam and N.A. Wong, alumnus V. Iddamsetty, grad students K. J. Hendargo and J Wang, undergrad A. Dubey, alumnus Y. Zhang, Dr. Medrano-Soto and Dr. Saier just published a paper in the journal PLoS ONE. The title is: "Comparative...