Welcome to the Saier Lab

Our laboratory takes a multidisciplinary approach to science, using biochemical, molecular genetic, physiological, and bioinformatic approaches. We have three primary research interests, one concerned with transcriptional and metabolic regulation in bacteria, a second with transport protein evolution, and a third with the recently identified process of transposon-mediated directed mutation. We also created and now maintain the Transporter Classification DataBase (TCDB), which was adopted by the International Union of Biochemistry and Molecular Biology (IUBMB) as the primary source of information relating to molecular transport.

 

Our Research

About us

Dr. Milton Saier is the head of the laboratory. The lab has two main branches: the wet lab (led by Dr. Zhongge Zhang) and the dry lab (led by Dr. Arturo Medrano-Soto). The progress of our experimental and bioinformatic projects depends on the work and interaction within our wonderfully eclectic team of researchers, talented students, visiting scholars and external collaborators. For more details, please visit our Research and Publications pages. The software developed and maintained by our bioinformatics team is available in our GitHub repository and our web applications are available in our BioTools page, Please, do not hesitate to contact us If you have any questions/requests or if you would like to give us  feedback.

Latest News

Hot off the press

Hot off the press

Our collaborator Dr. Zafar and  Dr. Saier just published a review in the journal Gut Microbes. In this review, they studied gut bacteria from the species Bacteroides and their role on health and disease. The title is "Gut Bacteroides species in health and disease"....

Hot off the press

Hot off the press

Grad student Nicholas Wong and Dr. Saier just published a review in the International Journal of Molecular Sciences about the infection cycle of SARS-coronavirus with emphasis on the role played by viral membrane proteins. The title is: "The SARS-Coronavirus Infection...

MSc degree obtained

MSc degree obtained

Congratulations to our grad student Daniel Tyler for a successful defense of his Master's thesis on Jan 28, 2021.  The title of his thesis is "Discovery and Characterization of the Phospholemman/SIMP/Viroporin (PSV) Superfamily". Abstract Determining the relatedness...