Publications

Find below our peer-reviewed publications since 2015. For a more complete list of about 600 papers, please click on your favorite source:

  • Chowdhury S, Hepper S, Lodi MK, Saier MH, Jr., Uetz P. The Protein Interactome of Glycolysis in Escherichia coli. (2021). Proteomes. 9(2):16. DOI: 10.3390/proteomes9020016. PMID: 33917325; PMCID: PMC8167557.

 

  • Russum S, Lam KJK, Wong NA, Iddamsetty V, Hendargo KJ, Wang J, Dubey A, Zhang Y, Medrano-Soto A, Saier MH, Jr. Comparative population genomic analyses of transporters within the Asgard archaeal superphylum. (2021). PLoS One. 16(3):e0247806. DOI: 10.1371/journal.pone.0247806. PMID: 33770091; PMCID: PMC7997004.

 

  • Zafar H, Saier MH, Jr. Gut Bacteroides species in health and disease. (2021). Gut Microbes. 13(1):1-20. DOI: 10.1080/19490976.2020.1848158. PMID: 33535896; PMCID: PMC7872030.

 

  • Wong NA, Saier MH, Jr. The SARS-Coronavirus Infection Cycle: A Survey of Viral Membrane Proteins, Their Functional Interactions and Pathogenesis. (2021). Int J Mol Sci. 22(3):1308. DOI: 10.3390/ijms22031308. PMID: 33525632; PMCID: PMC7865831.

 

  • Saier MH, Reddy VS, Moreno-Hagelsieb G, Hendargo KJ, Zhang Y, Iddamsetty V, Lam KJK, Tian N, Russum S, Wang J, Medrano-Soto A. The Transporter Classification Database (TCDB): 2021 update. (2021). Nucleic Acids Res. 49(D1):D461-D7. DOI: 10.1093/nar/gkaa1004. PMID: 33170213; PMCID: PMC7778945.

 

  • Zafar H, Saier MH, Jr. Comparative Genomics of the Transport Proteins of Ten Lactobacillus Strains. (2020). Genes (Basel). 11(10):1234. DOI: 10.3390/genes11101234. PMID: 33096690; PMCID: PMC7593918.

 

  • Wang SC, Davejan P, Hendargo KJ, Javadi-Razaz I, Chou A, Yee DC, Ghazi F, Lam KJK, Conn AM, Madrigal A, Medrano-Soto A, Saier MH, Jr. Expansion of the Major Facilitator Superfamily (MFS) to include novel transporters as well as transmembrane-acting enzymes. (2020). Biochim Biophys Acta Biomembr. 1862(9):183277. DOI: 10.1016/j.bbamem.2020.183277. PMID: 32205149; PMCID: PMC7939043.

 

  • Reddy BL, Saier MHJ. The Causal Relationship between Eating Animals and Viral Epidemics. (2020). Microb Physiol. 30(1-6):2-8. DOI: 10.1159/000511192. PMID: 32957108; PMCID: PMC7573891.

 

  • Medrano-Soto A, Ghazi F, Hendargo KJ, Moreno-Hagelsieb G, Myers S, Saier MH, Jr. Expansion of the Transporter-Opsin-G protein-coupled receptor superfamily with five new protein families. (2020). PLoS One. 15(4):e0231085. DOI: 10.1371/journal.pone.0231085. PMID: 32320418; PMCID: PMC7176098.

 

  • Aboulwafa M, Zhang Z, Saier MH, Jr. Protein-Protein Interactions in the Cytoplasmic Membrane of Escherichia coli: Influence of the Overexpression of Diverse Transporter-Encoding Genes on the Activities of PTS Sugar Uptake Systems. (2020). Microb Physiol. 30(1-6):36-49. DOI: 10.1159/000510257. PMID: 32998150; PMCID: PMC7717556.

 

  • Saier MH, Jr. Understanding the Genetic Code. (2019). J Bacteriol. 201(15):e00091-19. DOI: 10.1128/JB.00091-19. PMID: 31010904; PMCID: PMC6620406.

 

  • Rodionova IA, Heidari Tajabadi F, Zhang Z, Rodionov DA, Saier MH, Jr. A Riboflavin Transporter in Bdellovibrio exovorous JSS. (2019). J Mol Microbiol Biotechnol. 29(1-6):27-34. DOI: 10.1159/000501354. PMID: 31509826; PMCID: PMC7064401.

 

  • Maity K, Heumann JM, McGrath AP, Kopcho NJ, Hsu PK, Lee CW, Mapes JH, Garza D, Krishnan S, Morgan GP, Hendargo KJ, Klose T, Rees SD, Medrano-Soto A, Saier MH, Jr., Pineros M, Komives EA, Schroeder JI, Chang G, Stowell MHB. Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating. (2019). Proc Natl Acad Sci U S A. 116(28):14309-18. DOI: 10.1073/pnas.1900774116. PMID: 31227607; PMCID: PMC6628804.

 

  • Buyuktimkin B, Zafar H, Saier MH, Jr. Comparative genomics of the transportome of Ten Treponema species. (2019). Microb Pathog. 132:87-99. DOI: 10.1016/j.micpath.2019.04.034. PMID: 31029716; PMCID: PMC7085940.

 

  • Aboulwafa M, Zhang Z, Saier MH, Jr. Protein:Protein interactions in the cytoplasmic membrane apparently influencing sugar transport and phosphorylation activities of the E. coli phosphotransferase system. (2019). PLoS One. 14(11):e0219332. DOI: 10.1371/journal.pone.0219332. PMID: 31751341; PMCID: PMC6872149.

 

  • Zafar H, Saier MH, Jr. Comparative genomics of transport proteins in seven Bacteroides species. (2018). PLoS One. 13(12):e0208151. DOI: 10.1371/journal.pone.0208151. PMID: 30517169; PMCID: PMC6281302.

 

  • Rodionova IA, Goodacre N, Do J, Hosseinnia A, Babu M, Uetz P, Saier MH, Jr. The uridylyltransferase GlnD and tRNA modification GTPase MnmE allosterically control Escherichia coli folylpoly-gamma-glutamate synthase FolC. (2018). J Biol Chem. 293(40):15725-32. DOI: 10.1074/jbc.RA118.004425. PMID: 30089654; PMCID: PMC6177579.

 

  • Rodionova IA, Goodacre N, Babu M, Emili A, Uetz P, Saier MH, Jr. The Nitrogen Regulatory PII Protein (GlnB) and N-Acetylglucosamine 6-Phosphate Epimerase (NanE) Allosterically Activate Glucosamine 6-Phosphate Deaminase (NagB) in Escherichia coli. (2018). J Bacteriol. 200(5):e00691-17. DOI: 10.1128/JB.00691-17. PMID: 29229699; PMCID: PMC5809692.

 

  • Medrano-Soto A, Moreno-Hagelsieb G, McLaughlin D, Ye ZS, Hendargo KJ, Saier MH, Jr. Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases. (2018). PLoS One. 13(3):e0192851. DOI: 10.1371/journal.pone.0192851. PMID: 29579047; PMCID: PMC5868767.

 

  • Zhang Z, Kukita C, Humayun MZ, Saier MH. Environment-directed activation of the Escherichia coli flhDC operon by transposons. (2017). Microbiology (Reading). 163(4):554-69. DOI: 10.1099/mic.0.000426. PMID: 28100305; PMCID: PMC5775904.

 

  • Vastermark A, Driker A, Weng J, Li X, Wang J, Saier MH, Jr. Difference distance map data of alternative crystal forms of UlaA. (2017). Data Brief. 10:198-201. DOI: 10.1016/j.dib.2016.11.087. PMID: 27995154; PMCID: PMC5154960.

 

  • Saier MH, Jr., Trevors JT. Science, Innovation and the Future of Humanity. (2017). J Mol Microbiol Biotechnol. 27(2):128-32. DOI: 10.1159/000467401. PMID: 28448972; PMCID: PMC5804353.

 

  • Saier MH, Jr., Kukita C, Zhang Z. Transposon-mediated directed mutation in bacteria and eukaryotes. (2017). Front Biosci (Landmark Ed). 22:1458-68. DOI: 10.2741/4553. PMID: 28199212; PMCID: PMC5820026.

 

  • Rodionova IA, Zhang Z, Mehla J, Goodacre N, Babu M, Emili A, Uetz P, Saier MH, Jr. The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism by directly interacting with multiple enzymes in Escherichia coli. (2017). J Biol Chem. 292(34):14250-7. DOI: 10.1074/jbc.M117.795294. PMID: 28634232; PMCID: PMC5572926.

 

  • Moreno-Hagelsieb G, Vitug B, Medrano-Soto A, Saier MH, Jr. The Membrane Attack Complex/Perforin Superfamily. (2017). J Mol Microbiol Biotechnol. 27(4):252-67. DOI: 10.1159/000481286. PMID: 29145176; PMCID: PMC5796659.

 

  • Lee J, Ghosh S, Saier MH, Jr. Comparative genomic analyses of transport proteins encoded within the red algae Chondrus crispus, Galdieria sulphuraria, and Cyanidioschyzon merolae. (2017). J Phycol. 53(3):503-21. DOI: 10.1111/jpy.12534. PMID: 28328149; PMCID: PMC5591647.

 

  • Humayun MZ, Zhang Z, Butcher AM, Moshayedi A, Saier MH, Jr. Hopping into a hot seat: Role of DNA structural features on IS5-mediated gene activation and inactivation under stress. (2017). PLoS One. 12(6):e0180156. DOI: 10.1371/journal.pone.0180156. PMID: 28666002; PMCID: PMC5493358.

 

  • Heidari Tajabadi F, Medrano-Soto A, Ahmadzadeh M, Salehi Jouzani G, Saier MH, Jr. Comparative Analyses of Transport Proteins Encoded within the Genomes of Bdellovibrio bacteriovorus HD100 and Bdellovibrio exovorus JSS. (2017). J Mol Microbiol Biotechnol. 27(6):332-49. DOI: 10.1159/000484563. PMID: 29212086; PMCID: PMC5823784.

 

  • Do J, Zafar H, Saier MH, Jr. Comparative genomics of transport proteins in probiotic and pathogenic Escherichia coli and Salmonella enterica strains. (2017). Microb Pathog. 107:106-15. DOI: 10.1016/j.micpath.2017.03.022. PMID: 28344124; PMCID: PMC5591646.

 

  • Chou A, Lee A, Hendargo KJ, Reddy VS, Shlykov MA, Kuppusamykrishnan H, Medrano-Soto A, Saier MH, Jr. Characterization of the Tetraspan Junctional Complex (4JC) superfamily. (2017). Biochim Biophys Acta Biomembr. 1859(3):402-14. DOI: 10.1016/j.bbamem.2016.11.015. PMID: 27916633; PMCID: PMC5292247.

 

  • Zhang Z, Saier MH, Jr. Transposon-mediated activation of the Escherichia coli glpFK operon is inhibited by specific DNA-binding proteins: Implications for stress-induced transposition events. (2016). Mutat Res. 793-794:22-31. DOI: 10.1016/j.mrfmmm.2016.10.003. PMID: 27810619; PMCID: PMC5136330.

 

  • Vastermark A, Saier MH, Jr. Time to Stop Holding the Elevator: A New Piece of the Transport Protein Mechanism Puzzle. (2016). Structure. 24(6):845-6. DOI: 10.1016/j.str.2016.05.010. PMID: 27276425; PMCID: PMC5899902.

 

  • Vastermark A, Driker A, Weng J, Li X, Wang J, Saier MH. The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism. (2016). J Struct Biol. 196(3):496-502. DOI: 10.1016/j.jsb.2016.10.002. PMID: 27720943; PMCID: PMC5118081.

 

  • Saier MH, Jr., Reddy VS, Tsu BV, Ahmed MS, Li C, Moreno-Hagelsieb G. The Transporter Classification Database (TCDB): recent advances. (2016). Nucleic Acids Res. 44(D1):D372-9. DOI: 10.1093/nar/gkv1103. PMID: 26546518; PMCID: PMC4702804.

 

  • Saier MH, Jr. Transport protein evolution deduced from analysis of sequence, topology and structure. (2016). Curr Opin Struct Biol. 38:9-17. DOI: 10.1016/j.sbi.2016.05.001. PMID: 27270239; PMCID: PMC5354534.

 

  • Reddy BL, Saier MH, Jr. Properties and Phylogeny of 76 Families of Bacterial and Eukaryotic Organellar Outer Membrane Pore-Forming Proteins. (2016). PLoS One. 11(4):e0152733. DOI: 10.1371/journal.pone.0152733. PMID: 27064789; PMCID: PMC4827864.

 

  • Kuppusamykrishnan H, Chau LM, Moreno-Hagelsieb G, Saier MH, Jr. Analysis of 58 Families of Holins Using a Novel Program, PhyST. (2016). J Mol Microbiol Biotechnol. 26(6):381-8. DOI: 10.1159/000448040. PMID: 27553295; PMCID: PMC5591648.

 

  • Buyuktimkin B, Saier MH, Jr. Comparative analyses of transport proteins encoded within the genomes of Leptospira species. (2016). Microb Pathog. 98:118-31. DOI: 10.1016/j.micpath.2016.06.013. PMID: 27296707; PMCID: PMC5317275.

 

  • Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH, Jr., Wu W, Nigam SK. Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs. (2015). PLoS One. 10(11):e0140569. DOI: 10.1371/journal.pone.0140569. PMID: 26536134; PMCID: PMC4633038.

 

  • Vastermark A, Driker A, Li J, Saier MH, Jr. Conserved movement of TMS11 between occluded conformations of LacY and XylE of the major facilitator superfamily suggests a similar hinge-like mechanism. (2015). Proteins. 83(4):735-45. DOI: 10.1002/prot.24755. PMID: 25586173; PMCID: PMC4368487.

 

  • Tsu BV, Saier MH, Jr. The LysE Superfamily of Transport Proteins Involved in Cell Physiology and Pathogenesis. (2015). PLoS One. 10(10):e0137184. DOI: 10.1371/journal.pone.0137184. PMID: 26474485; PMCID: PMC4608589.

 

  • Saier MH, Jr., Zhang Z. Control of Transposon-Mediated Directed Mutation by the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System. (2015). J Mol Microbiol Biotechnol. 25(2-3):226-33. DOI: 10.1159/000375375. PMID: 26159081; PMCID: PMC4511099.

 

  • Saier MH, Jr., Reddy BL. Holins in bacteria, eukaryotes, and archaea: multifunctional xenologues with potential biotechnological and biomedical applications. (2015). J Bacteriol. 197(1):7-17. DOI: 10.1128/JB.02046-14. PMID: 25157079; PMCID: PMC4288690.

 

  • Saier MH, Jr. The Bacterial Phosphotransferase System: New Frontiers 50 Years after Its Discovery. (2015). J Mol Microbiol Biotechnol. 25(2-3):73-8. DOI: 10.1159/000381215. PMID: 26159069; PMCID: PMC4512285.

 

  • Reddy BL, Saier MH. Autism and our intestinal microbiota. (2015). J Mol Microbiol Biotechnol. 25(1):51-5. DOI: 10.1159/000375303. PMID: 25792275.

 

  • Kumar U, Saier MH, Jr. Comparative genomic analysis of integral membrane transport proteins in ciliates. (2015). J Eukaryot Microbiol. 62(2):167-87. DOI: 10.1111/jeu.12156. PMID: 25099884.

 

  • Chiang Z, Vastermark A, Punta M, Coggill PC, Mistry J, Finn RD, Saier MH, Jr. The complexity, challenges and benefits of comparing two transporter classification systems in TCDB and Pfam. (2015). Brief Bioinform. 16(5):865-72. DOI: 10.1093/bib/bbu053. PMID: 25614388; PMCID: PMC4570203.

 

  • Buyuktimkin B, Saier MH, Jr. Comparative genomic analyses of transport proteins encoded within the genomes of Leptospira species. (2015). Microb Pathog. 88:52-64. DOI: 10.1016/j.micpath.2015.07.019. PMID: 26247102; PMCID: PMC4601928.

 

  • Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ, Craik DJ, Finn RD, Gloriam D, Haft DH, Henrissat B, Holliday GL, Isberg V, Kaas Q, Landsman D, Lenfant N, Manning G, Nagano N, Srinivasan N, O’Donovan C, Pruitt KD, Sowdhamini R, Rawlings ND, Saier MH, Jr., Sharman JL, Spedding M, Tsirigos KD, Vastermark A, Vriend G. Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. (2015). Database (Oxford). 2015:bav063. DOI: 10.1093/database/bav063. PMID: 26284514; PMCID: PMC4499208.